Publications Repository - Helmholtz-Zentrum Dresden-Rossendorf
2 PublicationsASL spatial coefficient of variance predicts increased white matter hyperintensities volume over time in cognitively unimpaired subjects
Padrela, B.; Collij, L. E.; Lorenzini, L.; Ingala, S.; Sudre, C.; Visser, P. J.; Den Braber, A.; Barkhof, F.; Petr, J.; Mutsaerts, H. J. M. M.
Abstract
Arterial transit artifacts (ATAs) in arterial spin labeling (ASL) images are common in populations with prolonged arterial transit time (ATT) and may be associated with vascular insufficiency. The spatial coefficient of variance (sCoV) of ASL images can quantify the presence of these artifacts. Vascular insufficiency could contribute to the development of white matter hyperintensities (WMH), a common marker of cerebral small vessel disease. We demonstrated that baseline sCoV of CBF is associated with WMH at baseline and predicts WMH volume change, in a cognitively unimpaired population of 88 subjects.
Involved research facilities
- PET-Center
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Contribution to proceedings
2023 ISMRM & ISMRT Annual Meeting & Exhibition, 03.06.2023, Toronto, Canada
ISMRM '23: Proceedings of the ISMRM 31th Annual Meeting & Exhibition, 0580 -
Poster
2023 ISMRM & ISMRT Annual Meeting & Exhibition, 03.06.2023, Toronto, Canada
Permalink: https://www.hzdr.de/publications/Publ-38144
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