Publications Repository - Helmholtz-Zentrum Dresden-Rossendorf
1 PublicationP1802 - Universal Building Blocks for Radiolabeling
Abstract
The present invention describes novel chelators (multidentate ligands) and precompounds for complexation of radiometals and non-radioactive counterparts, for use in radiopharmacy. The invention includes a process and a kit involving such chelators.
Active moieties directing to a pharmaceutical target (such as peptides or proteins) can be attached to the chelator very easily via the so called “click-chemistry” forming a triazole-ring moiety. The aromatic triazole-nitrogen itself acts as a new and “soft” nucleophilic site enabling for complexation of various radiometals or non-radioactive counterparts. The chelators are capable of fast complexation at low temperature.
-
Patent
PCT/EP2019/054954 - Offenlegung 06.09.2019; Nachanmeldungen: EP
Permalink: https://www.hzdr.de/publications/Publ-31180
Years: 2023 2022 2021 2020 2019 2018 2017 2016 2015