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1 PublicationEffective coupling of Re/Tc-MAG3 complexes with amines and nucleobases in aprotic solvents.
Kniess, T.; Noll, S.; Noll, B.; Spies, H.; Johannsen, B.
Abstract
The coupling of Re- and 99mTc-MAG3 complexes with amines and nucleobases was carried out with good yields using O-(benzotriazol-1-yl-)N,N,N',N'-tetramethyl-
uronium-tetrafluoroborate (TBTU), and base in polar aprotic solvents (NMP, DMF, DMSO). The one step reaction followed by simple gel chromatography makes the method well appropriate for preparations at the low no-carrier-added level of technetium-99m.
Keywords: Re/Tc-MAG3; nucleobases; coupling; TBTU
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Journal of Radioanalytical and Nuclear Chemistry, 240, No. 2 (1999), 657-660
DOI: 10.1007/BF02349428
Cited 3 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-1824
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