Publications Repository - Helmholtz-Zentrum Dresden-Rossendorf

Owing to their antiviral and antitumoral properties polyoxometalates (POMs) are gaining in importance in the development of therapeutic agents. Such cluster molecules possessing a multitude of metal atoms might be took advantage in view of cancer treatment by photon activation therapy (PAT). In this nexus it is necessary to meet some requirements. So, POMs must have sufficient stability under physiological conditions. Furthermore, highly efficient transportation into cells, and finally the interaction with DNA is essential. The encapsulation of POMs by aminosaccharides seems to be a promising way to achieve that. In our previous study we reported about the possibility conditions to form complexes between various metal-oxoanions and sorbents having different diol-ligands. Now, we want to report the binding and sorption behavior of selected aminosaccharides towards polyoxotungstates.