Publications Repository - Helmholtz-Zentrum Dresden-Rossendorf
2 PublicationsHeterogeneity of ASL perfusion MRI in low-grade paediatric glioma as imaging biomarker to assess treatment effect
Alic, L.; Willekens, S. C.; Mutsaerts, H.-J. M. M.; Petr, J.; Schouten-Van Meeteren, N. A. Y. N.; Lequin, M. M. H.; Wiegers, E. E. C.
Abstract
ASL-MRI is reported as an option to assess potentially heterogeneous physiological processes important for tumour treatment. Therefore, we explored the heterogeneity in normalised CBF as an imaging biomarker for assessment of treatment effect in pLGG. There is a noticeable effect of chemotherapy observed as a change in texture of healthy appearing brain tissue. A high difference in texture between treated and non-treated patients for non-enhancing tumour part is observed, suggesting that texture, based on co-occurrence matrices, is suitable as an imaging biomarker for assessment of treatment effect in pLGG.
Involved research facilities
- PET-Center
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Contribution to proceedings
ISMRM '22: Proceedings of the ISMRM 30th Annual Meeting & Exhibition, 07.-12.05.2022, London, United Kingdom -
Poster
ISMRM '22: Proceedings of the ISMRM 30th Annual Meeting & Exhibition, 07.-12.05.2022, London, United Kingdom
Permalink: https://www.hzdr.de/publications/Publ-34739
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