Publications Repository - Helmholtz-Zentrum Dresden-Rossendorf
1 PublicationPolyethyleneimine Methylenecarboxylate: a macromolecular DTPA analogue to chelate plutonium(IV)
Lahrouch, F.; Siberchiot, B.; Leost, L.; Aupiais, J.; Rossberg, A.; Hennig, C.; Den Auwer, C.; Di Giorgio, C.
Abstract
Up until now, molecular chelating agents, such as the diethylenetriamine pentaacetic acid (DTPA) have been the standard methode for actinide human decorporation. Active mainly in blood serum, their distribution within the body is thus limited. In order to treat a wider range of organs affected by plutonium contamination, a potential new class of macromolecular decorporation agents is being studied. Polyethyleneimine methylenecarboxylate (PEI-MC) is one such example. It is being considered here because of its capacity for targeting the liver and bones.
Keywords: Polyethyleneimine methylenecarboxylate; actinides; decorporation; EXAFS
Involved research facilities
- Rossendorf Beamline at ESRF DOI: 10.1107/S1600577520014265
Related publications
- DOI: 10.1107/S1600577520014265 is cited by this (Id 27728) publication
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Chemical Communications 54(2018)83, 11705-11708
DOI: 10.1039/c8cc05206a
Cited 6 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-27728
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