Publications Repository - Helmholtz-Zentrum Dresden-Rossendorf
1 PublicationDevelopment of a High-Affinity PET Radioligand for Imaging Cannabinoid Subtype 2 Receptor
Moldovan, R.-P.; Teodoro, R.; Deuther-Conrad, W.; Kranz, M.; Wang, Y.; Nakano, M.; Valentine, H.; Fischer, S.; Pomper, M.; Wong, D. F.; Dannals, R. F.; Brust, P.; Horti, A. G.
Abstract
Cannabinoid receptors type 2 (CB2) represent a target with increasing importance for neuroimaging due to its upregulation under various pathological conditions. Encouraged by preliminary results obtained with 11C.
Keywords: Cannabinoid receptor type 2; Neuroinflammation; A-836339; Radiofluorination; Positron emission tomography
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Journal of Medicinal Chemistry 59(2016)17, 7840-7855
DOI: 10.1021/acs.jmedchem.6b00554
Cited 49 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-23345
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