Publications Repository - Helmholtz-Zentrum Dresden-Rossendorf
1 PublicationBiomimetic Magnetic Silk Scaffolds
Samal, S. K.; Dash, M.; Shelyakova, T.; Declercq, H. A.; Uhlarz, M.; Banobre-Lopez, M.; Dubruel, P.; Cornelissen, M.; Herrmannsdörfer, T.; Rivas, J.; Padeletti, G.; de Smedt, S.; Braeckmans, K.; Kaplan, D. L.; Dediu, V. A.
Abstract
Magnetic silk fibroin protein (SFP) scaffolds integrating magnetic materials and featuring magnetic gradients were prepared for potential utility in magnetic-field assisted tissue engineering. Magnetic nanoparticles (MNPs) were introduced into SFP scaffolds via dip-coating methods, resulting in magnetic SFP scaffolds with different strengths of magnetization. Magnetic SFP scaffolds showed excellent hyperthermia properties achieving temperature increases up to 8 °C in about 100 s. The scaffolds were not toxic to osteogenic cells and improved cell adhesion and proliferation. These findings suggest that tailored magnetized silk-based biomaterials can be engineered with interesting features for biomaterials and tissue-engineering applications.
Involved research facilities
- High Magnetic Field Laboratory (HLD)
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ACS Applied Materials and Interfaces 7(2015), 6282-6292
DOI: 10.1021/acsami.5b00529
ISSN: 1944-8244
Cited 53 times in Scopus
Permalink: https://www.hzdr.de/publications/Publ-22176
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