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Radiolabelling of proteins with fluorine-18 via click chemistry

Ramenda, T.; Knieß, T.; Bergmann, R.; Steinbach, J.; Wüst, F.

Abstract

The study describes for the first time the application of Cu(I)-mediated 1,3-dipolar [3+2]cycloaddition for the labelling of proteins with the short-lived positron emitter fluorine-18 as exemplified with azide-functionalized human serum albumin (HSA).

Permalink: https://www.hzdr.de/publications/Publ-13504


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