Publications of Institute of Radiopharmaceutical Cancer Research
262 Publications2009
Fluorine-18 radiolabeling of native and oxidized proteins: An important tool in the pathophysiologists toolbox
Pietzsch, J.; Wuest, F.
- Chimica Oggi - Chemistry Today 27(2009), 12-14
Fluorine-18-radiolabeled S100A12: a potential probe for functional characterization of inflammatory processes in vivo
Hoppmann, S.; Richter, S.; Steinbach, J.; Pietzsch, J.
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Inflammation Research 58(2009)Suppl. 2, S145-S146
ISSN: 1023-3830
Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives
Wuest, F.; Tang, X.; Knieß, T.; Pietzsch, J.; Suresh, M.
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Bioorganic & Medicinal Chemistry 17(2009), 1146-1151
DOI: 10.1016/j.bmc.2008.12.032
Radiosynthesis and radiopharmacological evaluation of [N-methyl-11C]Org 34850 as a glucocorticoid receptor (GR)-binding radiotracer
Wüst, F.; Knieß, T.; Henry, B.; Peeters, B. W. M. M.; Wiegerinck, P. H. G.; et al. (7 authors)
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Applied Radiation and Isotopes 67(2009), 308-312
DOI: 10.1016/j.apradiso.2008.10.014
Prediabetic and diabetic in vivo modification of circulating low density lipoprotein attenuates its stimulatory effect on adrenal mineralocorticoid secretion
Kopprasch, S.; Pietzsch, J.; Ansurudeen, I.; Graessler, J.; Krug, A. W.; et al. (7 authors)
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Journal of Endocrinology 200(2009), 45-52
DOI: 10.1677/JOE-08-0293
Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 2: Subcellular distribution
Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; et al. (13 authors)
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Nuclear Medicine and Biology 36(2009), 845-852
DOI: 10.1016/j.nucmedbio.2009.06.003
Validation of 99mTc-labeled "4+1" fatty acids for myocardial metabolism and flow imaging Part 1: Myocardial extraction and biodistribution
Mirtschink, P.; Stehr, S. N.; Walther, M.; Pietzsch, J.; Bergmann, R.; et al. (13 authors)
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Nuclear Medicine and Biology 36(2009), 833-843
DOI: 10.1016/j.nucmedbio.2009.06.009
Cell cycle regulating kinase Cdk4 as a potential target for tumor cell treatment and tumor imaging
Graf, F.; Köhler, L.; Knieß, T.; Wüst, F.; Mosch, B.; et al. (6 authors)
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Journal of Oncology 2009(2009), 106378
DOI: 10.1155/2009/106378
Human S100A12: a novel key player in inflammation?
Pietzsch, J.; Hoppmann, S.
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Amino Acids 36(2009), 381-389
DOI: 10.1007/s00726-008-0097-7
ISSN: 0939-4451 (Print) 14
Systematic comparison of two novel thiol-reactive prosthetic groups for 18F labeling of peptides and proteins with the acylation agent succinimidyl-4-[18F]fluorobenzoate [18F]SFB
Wüst, F.; Köhler, L.; Berndt, M.; Pietzsch, J.
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Amino Acids 36(2009), 283-295
ISSN: 0939-4451
2008
Effects of pioglitazone and/or simvastatin on low density lipoprotein subfractions in non-diabetic patients with high cardiovascular risk: A sub-analysis from the PIOSTAT study
Leonhardt, W.; Pfützner, A.; Müller, J.; Pietzsch, J.; Forst, T.; et al. (8 authors)
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Atherosclerosis 201(2008), 155-162
DOI: 10.1016/j.atherosclerosis.2008.01.007
Synthesis and evaluation in vitro and in vivo of a 11C-labeled cyclooxygenase-2 (COX-2) inhibitor
Wüst, F.; Knieß, T.; Bergmann, R.; Pietzsch, J.
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Bioorganic & Medicinal Chemistry 16(2008), 7662-7670
DOI: 10.1016/j.bmc.2008.07.016
Yttrium-86-labelled human serum albumin microspheres: relation of surface structure with in vivo stability
Schiller, E.; Bergmann, R.; Pietzsch, J.; Noll, B.; Sterger, A.; et al. (8 authors)
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Nuclear Medicine and Biology 35(2008), 227-232
DOI: 10.1016/j.nucmedbio.2007.10.008
Synthesis and Application of [18F]FDG-maleimidehexyloxime ([18F]FDG-MHO): A [18F]FDG-based Prosthetic Group for the Chemoselective 18F-Labeling of Peptides and Proteins
Wüst, F.; Berndt, M.; Bergmann, R.; van den Hoff, J.; Pietzsch, J.
- Bioconjugate Chemistry 19(2008)6, 1202-1210
Radiolabeled glucocorticoids as molecular probes for imaging brain glucocorticoid receptors by means of positron-emission-tomography (PET)
Steiniger, B.; Knieß, T.; Bergmann, R.; Pietzsch, J.; Wüst, F.
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Mini-Reviews in Medicinal Chemistry 8(2008)7, 728-739
ISSN: 1389-5575
Radiosynthesis of n.c.a. sodium [18F]fluoroacetate and radiopharmacological characterization in rats and tumour-xenografted mice
Richter, S.; Bergmann, R.; Pietzsch, J.; Beuthien-Baumann, B.; Wüst, F.
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Current Radiopharmaceuticals 1(2008)2, 103-109
ISSN: 1874-4710
Expression, purification and fluorine-18 radiolabeling of recombinant S100 proteins - potential probes for molecular imaging of receptor for advanced glycation endproducts (RAGE) in vivo
Hoppmann, S.; Haase, C.; Richter, S.; Pietzsch, J.
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Protein Expression and Purification 57(2008)2, 143-152
DOI: 10.1016/j.pep.2007.10.009
Glycoxidation of low-density lipoprotein in impaired glucose tolerance: implications for the pathogenesis of diabetic vascular disease
Kopprasch, S.; Graessler, J.; Bornstein, S. R.; Pietzsch, J.
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Vascular Disease Prevention 5(2008), 24-28
ISSN: 1567-2700
Localized proton magnetic resonance spectroscopy of lipids in adipose tissue at high spatial resolution in mice in vivo
Strobel, K.; van den Hoff, J.; Pietzsch, J.
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Journal of Lipid Research 49(2008), 473-480
DOI: 10.1194/jlr.D700024-JLR200
Modified 4+1 Mixed Ligand Technetium Labeled Fatty Acids for Myocardial Imaging: Evaluation of Myocardial Uptake and Biodistribution
Mirtschink, P.; Stehr, S. N.; Pietzsch, H.-J.; Bergmann, R.; Pietzsch, J.; et al. (12 authors)
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Bioconjugate Chemistry 19(2008), 97-108
DOI: 10.1021/bc700164c
2007
Factors influencing the formation of small dense low-density lipoprotein particles in dependence on the presence of the metabolic syndrome and on the degree of glucose intolerance
Julius, U.; Dittrich, M.; Pietzsch, J.
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International Journal of Clinical Practice 61(2007)11, 1798-1804
DOI: 10.1111/j.1742-1241.2007.01507.x
Myocardial uptake and biodistribution of newly designed technetium-labelled fatty acid analogues
Heintz, A. C.; Jung, C. M.; Stehr, S. N.; Mirtschink, P.; Walther, M.; et al. (12 authors)
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Nuclear Medicine Communications 28(2007)8, 637-647
ISSN: 0143-3636
Experimental hypoxia is a potent stimulus for radiotracer uptake in vitro: Comparison of different tumor cells and primary endothelial cells
Oswald, J.; Treite, F.; Haase, C.; Kampfrath, T.; Mäding, P.; et al. (8 authors)
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Cancer Letters 254(2007), 102-110
DOI: 10.1016/j.canlet.2007.02.016
[18F]FBAM and [18F]FBOM: Novel Thiol-reactive prosthetic groups derived from 4-[18F]fluorobenzaldehyde
Vogler, L.; Berndt, M.; Pietzsch, J.; Wüst, F.
- Journal of Labelled Compounds and Radiopharmaceuticals 50(2007), 1276-1286
L-Type Amino Acid Transporters LAT1 and LAT4 in Cancer: Uptake of 3-O- Methyl-6-18F-Fluoro-L-Dopa (18F-OMFD) in Human Adenocarcinoma and Squamous Cell Carcinoma in vitro and in vivo
Haase, C.; Bergmann, R.; Füchtner, F.; Hoepping, A.; Pietzsch, J.
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Journal of Nuclear Medicine 48(2007)12, 2063-2071
DOI: 10.2967/jnumed.107.043620
Glycoxidised LDL isolated from subjects with impaired glucose tolerance increases CD36 and peroxisome proliferator-activator receptor gamma gene expression in macrophages
Graessler, J.; Pietzsch, J.; Westendorf, T.; Julius, U.; Bornstein, S. R.; et al. (6 authors)
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Diabetologia 50(2007)5, 1080-1088
DOI: 10.1007/s00125-007-0645-9
ISSN: 0012-186X
Lipid transfer protein activities in subjects with impaired glucose tolerance
Julius, U.; Jauhiainen, M.; Ehnholm, C.; Pietzsch, J.
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Clinical Chemistry and Laboratory Medicine 45(2007)2, 237-243
ISSN: 1434-6621
Labeling of low-density lipoproteins using the 18F-labeled thiol-reactive reagent N-[6-(4-[18F]fluorobenzylidene)aminooxyhexyl]maleimide [18F]FBAM
Berndt, M.; Pietzsch, J.; Wüst, F.
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Nuclear Medicine and Biology 34(2007), 5-15
DOI: 10.1016/j.nucmedbio.2006.09.009
Synthesis of 18F-labelled stilbenes from 4-[18F]fluorobenzaldehyde using the Horner-Wadsworth-Emmons reaction
Gester, S.; Pietzsch, J.; Wüst, F.
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Journal of Labelled Compounds and Radiopharmaceuticals 50(2007)2, 105-113
DOI: 10.1002/jlcr.1172
Synthesis and radiopharmacological characterization of [11C]AL-438 as a nonsteroidal ligand for imaging brain glucocorticoid receptors
Wüst, F.; Knieß, T.; Bergmann, R.; Henry, B.; Pietzsch, J.
- Bioorganic & Medicinal Chemistry Letters 17(2007), 4035-4039
Synthesis and biological evaluation of a new type of 99mTechnetium-labeled fatty acid for myocardial metabolism imaging
Walther, M.; Jung, C.; Bergmann, R.; Pietzsch, J.; Rode, K.; et al. (15 authors)
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Bioconjugate Chemistry 18(2007), 216-230
ISSN: 10.1021/bc0601222
2006
Neurotensin Receptors in Adeno- and Squamous Cell Carcinoma
Haase, C.; Bergmann, R.; Oswald, J.; Zips, D.; Pietzsch, J.
- Anticancer Research 26(2006), 3527-3534
Biodistribution and catabolism of 18F-labeled N-epsilon-fructoselysine as a model of Amadori products
Hultsch, C.; Hellwig, M.; Pawelke, B.; Bergmann, R.; Rode, K.; et al. (8 authors)
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Nuclear Medicine and Biology 33(2006), 865-873
DOI: 10.1016/j.nucmedbio.2006.07.007
2005
Positron emission tomography in food sciences
Pietzsch, J.; van den Hoff, J.
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Amino Acids 29(2005)4, 303-305
DOI: 10.1007/s00726-005-0198-5
ISSN: 0939-4451
Small animal positron emission tomography in food sciences
Bergmann, R.; Pietzsch, J.
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Amino Acids 29(2005)4, 355-376
DOI: 10.1007/s00726-005-0237-2
ISSN: 0939-4451
Biodistribution and catabolism of 18F-labelled isopeptide N (varepsilon)-(gamma-glutamyl)-L-lysine
Hultsch, C.; Bergmann, R.; Pawelke, B.; Pietzsch, J.; Wüst, F.; et al. (7 authors)
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Amino Acids 29(2005)4, 405-413
DOI: 10.1007/s00726-005-0204-y
ISSN: 0939-4451
Catabolism of native and oxidized low density lipoproteins (LDL): in vivo insights from small animal positron emission tomography studies
Pietzsch, J.; Bergmann, R.; Wüst, F.; Pawelke, B.; Hultsch, C.; et al. (6 authors)
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Amino Acids 29(2005)4, 389-404
DOI: 10.1007/s00726-005-0203-z
ISSN: 0939-4451
Glucose-Induced Enhancement of Hemin-Catalyzed LDL Oxidation In Vitro and In Vivo
Julius, U.; Pietzsch, J.
- Antioxidants and Redox Signaling 7(2005)11-12, 1507-1512
Pathological consequenses of systemic oxidative stress and dyslipidemia in impaired glucose tolerance and diabetes mellitus
Kopprasch, S.; Grässler, J.; Pietzsch, J.
- Trends in Cell & Molecular Biology 1(2005), 1-14
In vivo metabolism of oxidized low density lipoproteins: Insights from small animal positron emission tomography (PET) studies
Pietzsch, J.; Bergmann, R.; Wüst, F.; van den Hoff, J.
- Recent Research Developments in Molecular & Cellular Biochemistry 2(2005), 153-177
Synthesis and biodistribution of an 18F-labelled resveratrol derivative for small animal positron emission tomography (PET)
Gester, S.; Wüst, F.; Pawelke, B.; Bergmann, R.; Pietzsch, J.
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Amino Acids 29(2005)4, 415-428
DOI: 10.1007/s00726-005-0205-x
ISSN: 0939-4451
2004
Fluorine-18 radiolabeling of low-density lipoproteins: a potential approach for characterization and differentiation of metabolism of native and oxidized low-density lipoproteins in vivo.
Pietzsch, J.; Bergmann, R.; Rode, K.; Hultsch, C.; Pawelke, B.; et al. (7 authors)
- Nuclear Medicine and Biology 31(2004), 1043-1050
3-O-Methyl-6-18F-Fluoro-L-Dopa, a New Tumor Imaging Agent: Investigation of Transport Mechanism In Vitro
Bergmann, R.; Pietzsch, J.; Füchtner, F.; Pawelke, B.; Beuthien-Baumann, B.; et al. (7 authors)
- Journal of Nuclear Medicine 45(2004), 2116-2122
The effect of garlic on arteriosclerotic nanoplaque formation and size
Siegel, G.; Malmsten, M.; Pietzsch, J.; Schmidt, A.; Buddecke, E.; et al. (8 authors)
- Phytomedicine 11(2004), 24-35
Oxidativ modifizierte Lipoproteine und deren Antikörper bei Patienten mit Antiphospholipid-Syndrom
Roch, B.; Kopprasch, S.; Pietzsch, J.; Schröder, H.
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Zeitschrift für Rheumatologie (2004) 63(2004), 331-337
DOI: 10.1007/s00393-004-0601-8
The pivotal role of scavenger receptor CD36 and phagocyte-derived oxidants in oxidized low density lipoprotein-induced adhesion to endothelial cells
Kopprasch, S.; Pietzsch, J.; Westendorf, T.; Kruse, H.-J.; Graessler, J.
- International Journal of Biochemistry and Cell Biology 36(2004)3, 460-471
The protective effects of HDL and its constituents against neutrophil respiratory bust activation by hypochlirite-oxidized LDL
Kopprasch, S.; Pietzsch, J.; Graessler, J.
- Molecular and Cellular Biochemistry 258(2004), 121-127
Analysis of non-protein amino acids as specific markers of low density lipoprotein apolipoprotein B-100 oxidation in human atherosclerotic lesions: the use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and GC-MS
Pietzsch, J.; Bergmann, R.; Kopprasch, S.
- Spectroscopy 18(2004),177-183
Analysis of 6-hydroxy-2-aminocaproic acid (HACA) as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry
Pietzsch, J.; Bergmann, R.
- Amino Acids 26(2004), 45-51
2003
Validation of different chemilumigenic substrates for detecting extracellular generation of reactive oxygen species by phagocytes and endothelial cells
Kopprasch, S.; Pietzsch, J.; Graessler, J.
- Luminescence (2003) 18: 268-273
Fortschritte in der Aminosäureanalytik: N(O,S)-Ethoxycarbonyl-(trifluoro)ethylester-Derivate
Pietzsch, J.
- Bioforum 10/2003, 643-645
Measurement of 5-hydroxy-2-aminovaleric acid as a specific marker of iron-mediated oxidation of proline and arginine residues of low density lipoprotein aplipoprotein B-100 in human atherosclerotic lesions
Pietzsch, J.; Bergmann, R.
- J Clin Pathol (2003) 56: 622-623
Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 2)
Pietzsch, J.; Bergmann, R.; Wüst, F.
- Bioforum (2003) 6:384-385
Flavonoide: Wirkmechanismen und neue Anwendungsmöglichkeiten (Teil 1)
Pietzsch, J.; Bergmann, R.; Wüst, F.
- Bioforum (2003) 5: 289-291
Increased cholesteryl ester transfer protein (CETP) activity in impaired glucose tolerance: relationship to high density lipoprotein metabolism
Pietzsch, J.; Fücker, K.
- Croatian Medical Journal 44 (2): 171-177, 2003
Lack of association between serum paraoxonase (PON1) activities and increased oxidized LDL levels in impaired glucose tolerance and newly diagnosed diabetes mellitus
Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Gräßler, J.
- Journal of Clinical Endocrinology & Metabolism 2003; 88: 1711-1716
Analysis of 3-chlorotyrosine as a specific marker of protein oxidation: The use of N(O,S)-ethoxycarbonyl trifluoroethyl ester derivatives and gas chromatography/mass spectrometry
Pietzsch, J.; Kopprasch, S.; Bergmann, R.
- Rapid Commun. Mass Spectrom 17 (2003):767-770
2002
Intraindividual comparison of two extracorporeal LDL apheresis methods: lipidfiltration and HELP
Julius, U.; Metzler, W.; Pietzsch, J.; Fassbender, T.; Klingel, R.
- Int J Artif Organs 25 (2002): 1180-1188
In vivo evidence for increased oxidation of circulating LDL in impaired glucose tolerance
Kopprasch, S.; Pietzsch, J.; Kuhlisch, E.; Fuecker, K.; Temelkova-Kurktschiev, T.; et al. (9 authors)
- Diabetes 51 (2002) 3102-3106
Impaired glucose tolerance is not associated with lipid intolerance
Henkel, E.; Temelkova-Kurtschiev, T.; Köhler, C.; Pietzsch, J.; Leonhardt, W.; et al. (6 authors)
- Diab Nutr Metab 15 (2002) 84-90
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