Publikationen - Institut für Radiopharmazeutische Krebsforschung - Jahr 2014
66 Publikationen2014
Quantitative assessment of the asphericity of pretherapeutic FDG uptake as an independent predictor of outcome in NSCLC.
Apostolova, I.; Rogasch, J.; Buchert, R.; Wertzel, H.; Achenbach, H. J.; et al. (13 authors)
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BMC Cancer 14(2014), 896
DOI: 10.1186/1471-2407-14-896
The influence of different signal-to-background ratios on spatial resolution and F18-FDG-PET quantification using point spread function and time-of-flight reconstruction
Rogasch, J. M. M.; Hofheinz, F.; Lougovski, A.; Furth, C.; Ruf, J.; et al. (11 authors)
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EJNMMI Physics 1(2014)
DOI: 10.1186/2197-7364-1-12
Dual Role of B7 Costimulation in Obesity-Related Nonalcoholic Steatohepatitis and Metabolic Dysregulation
Chatzigeorgiou, A.; Chung, K.-J.; Garcia-Martin, R.; Alexaki, V.-I.; Klotzsche-Von Ameln, A.; et al. (22 authors)
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Hepatology 60(2014), 1196-1210
DOI: 10.1002/hep.27233
ISSN: 0270-9139
FDG PET/MR for the Assessment of Lymph Node Involvement in Lymphoma: Initial Results and Role of Diffusion-Weighted MR
Platzek, I.; Beuthien-Baumann, B.; Ordemann, R.; Maus, J.; Schramm, G.; et al. (9 authors)
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Academic Radiology 21(2014)10, 1314-1319
DOI: 10.1016/j.acra.2014.05.019
ISSN: 1076-6332
Preparation of 4-Halobenzoate Containing Phosphane Based Building Blocks for Labeling Reactions Using the Traceless Staudinger Ligation
Mamat, C.; Köckerling, M.
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Synthesis 46(2014)2, 387-394
DOI: 10.1055/s-0034-1379487
X-ray structure of 2-(diphenylphosphano)phenyl-4-(hydroxymethyl)benzoate
Mamat, C.; Flemming, A.; Köckerling, M.
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Acta Crystallographica Section E E70(2014), o1288-o1289
DOI: 10.1107/S1600536814024623
ISSN: 1600-5368
Organotypical vascular model for characterization of radioprotective compounds: Studies on antioxidant 2,3-diaryl-substituted indole-based cyclooxygenase-2 inhibitors
Ullm, S.; Laube, M.; Bechmann, N.; Knieß, T.; Pietzsch, J.
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Clinical Hemorheology and Microcirculation 58(2014), 281-295
DOI: 10.3233/CH-141902
Internal Dose Assessment of (-)-18F-Flubatine, Comparing Animal Model Datasets of Mice and Piglets with First-in-Human Results
Sattler, B.; Kranz, M.; Starke, A.; Wilke, S.; Donat, C. K.; et al. (15 authors)
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Journal of Nuclear Medicine 55(2014)11, 1885-1892
DOI: 10.2967/jnumed.114.137059
ISSN: 2159-662X
Redirection of CD4+ and CD8+ T lymphocytes via a novel antibody-based modular targeting system triggers efficient killing of PSCA+ prostate tumor cells
Arndt, C.; Feldmann, A.; Töpfer, K.; Koristka, S.; Cartellieri, M.; et al. (9 authors)
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The Prostate 74(2014), 1347-1358
DOI: 10.1002/pros.22851
Synthesis and evaluation of a 18F-labeled spirocyclic piperidine derivative as promising σ1 receptor imaging agent
Chen, Y.-Y.; Wang, X.; Zhang, J.-M.; Deuther-Conrad, W.; Zhang, X.-J.; et al. (12 authors)
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Bioorganic & Medicinal Chemistry 22(2014), 5270-5278
DOI: 10.1016/j.bmc.2014.08.003
Novel Cyclopentadienyl Tricarbonyl 99mTc Complexes Containing 1‑Piperonylpiperazine Moiety: Potential Imaging Probes for Sigma‑1 Receptors
Wang, X.; Li, D.; Deuther-Conrad, W.; Lu, J.; Xie, Y.; et al. (11 authors)
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Journal of Medicinal Chemistry 57(2014), 7113-7125
DOI: 10.1021/jm5009488
Characterization of circulating microparticle-associated CD39 family ecto-nucleotidases in human plasma
Jiang, Z. G.; Wu, Y.; Csizmadia, E.; Feldbrügge, L.; Enjyoji, K.; et al. (12 authors)
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Purinergic Signalling 10(2014), 611-618
DOI: 10.1007/s11302-014-9423-6
The Ti7-Containing, Tetrahedral 36-Tungsto-4-Arsenate(III)[Ti6(TiO6)(AsW9O33)4]20-
Wang, K.-Y.; Bassil, B. S.; Lin, Z. G.; Haider, A.; Cao, J.; et al. (8 authors)
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Dalton Transactions 43(2014), 16143-16146
DOI: 10.1039/c4dt02494j
Bispidines for dual imaging
Stephan, H.; Walther, M.; Fähnemann, S.; Ceroni, P.; Molloy, J.; et al. (10 authors)
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Chemistry - A European Journal 20(2014), 17011-17018
DOI: 10.1002/chem.201404086
2,3-Diaryl-substituted indole based COX-2 inhibitors as leads for imaging tracer development
Laube, M.; Tondera, C.; Sharma, S. K.; Bechmann, N.; Pietzsch, F.-J.; et al. (10 authors)
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RSC Advances 4(2014), 38726-38742
DOI: 10.1039/c4ra05650g
In Vivo Fluorescence Imaging and Urinary Monoamines as Surrogate Biomarkers of Disease Progression in a Mouse Model of Pheochromocytoma
Ullrich, M.; Bergmann, R.; Peitzsch, M.; Cartellieri, M.; Quin, N.; et al. (12 authors)
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Endocrinology 155(2014), 4149-4156
DOI: 10.1210/en.2014-1431
ISSN: 0013-7227
Biocompatibility and inflammatory response in vitro and in vivo to gelatin-based biomaterials with tailorable elastic properties
Ullm, S.; Krüger, A.; Tondera, C.; Gebauer, T. P.; Neffe, A. T.; et al. (8 authors)
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Biomaterials 35(2014), 9755-9766
DOI: 10.1016/j.biomaterials.2014.08.023
ISSN: 0142-9612
Adenosine activates brown adipose tissue and recruits beige adipocytes via A2A receptors
Gnad, T.; Scheibler, S.; von Kügelgen, I.; Scheele, C.; Kilic, A.; et al. (21 authors)
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Nature 516(2014), 395-399
DOI: 10.1038/nature13816
Asphericity of pretherapeutic tumour FDG uptake provides independent prognostic value in head-and-neck cancer
Apostolova, I.; Steffen, I. G.; Wedel, F.; Lougovski, A.; Marnitz, S.; et al. (10 authors)
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European Radiology 24(2014), 2077-2087
DOI: 10.1007/s00330-014-3269-8
Periacetabular bone metabolism following hip revision surgery. PET-based evaluation of allograft osteointegration.
Bernstein, P.; Beuthien-Baumann, B.; Kotzerke, J.; Hofheinz, F.; Zessin, J.; et al. (7 authors)
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Nuklearmedizin 53(2014), 147-154
DOI: 10.3413/Nukmed-0607-13-06
ISSN: 0029-5566
Zwitterionic-Coated "Stealth" Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System
Pombo Garcia, K.; Zarschler, K.; Barbaro, L.; Barreto, J. A.; O'Malley, W.; et al. (8 authors)
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Small 10(2014), 2516-2529
DOI: 10.1002/smll.201303540
ISSN: 1613-6810
Evaluation of metabolism, plasma protein binding and other biological parameters after administration of (−)-[18 F]Flubatine in humans
Patt, M.; Becker, G. A.; Grossmann, U.; Habermann, B.; Schildan, A.; et al. (17 authors)
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Nuclear Medicine and Biology 41(2014), 489-494
DOI: 10.1016/j.nucmedbio.2014.03.018
Assessment of the best N3− donors in preparation of [M(N)(PNP)]-based (M = 99mTc-; 188Re) target-specific radiopharmaceuticals: Comparison among succinic dihydrazide (SDH), N-methyl-S-methyl dithiocarbazate (HDTCZ) and PEGylated N-methyl-S-methyl dithiocarbazate (HO2C-PEG600-DTCZ)
Carta, D.; Jentschel, C.; Thieme, S.; Salvarese, N.; Morellato, N.; et al. (10 authors)
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Nuclear Medicine and Biology 41(2014), 570-581
DOI: 10.1016/j.nucmedbio.2014.04.126
Imaging of α7 nicotinic acetylcholine receptors in brain and cerebral vasculature of juvenile pigs with [18F]NS14490
Rötering, S.; Deuther-Conrad, W.; Cumming, P.; Donat, C. K.; Scheunemann, M.; et al. (12 authors)
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EJNMMI Research 4(2014), 1-11
DOI: 10.1186/s13550-014-0043-5
Bispidine dioxotetraaza macrocycles: a new class of bispidines for 64Cu PET imaging
Comba, P.; Kubeil, M.; Pietzsch, J.; Rudolf, H.; Stephan, H.; et al. (6 authors)
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Inorganic Chemistry 53(2014), 6698-6707
DOI: 10.1021/ic500476u
Radiofluorination and first radiopharmacological characterization of a SWLAY peptide-based ligand targeting EphA2
Pretze, M.; Mosch, B.; Bergmann, R.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)
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Journal of Labelled Compounds and Radiopharmaceuticals 57(2014), 660-665
DOI: 10.1002/jlcr.3237
Proinflammatory human 6-sulfo LacNAc-positive dendritic cells accumulate in intestinal acute graft-versus-host disease
Sommer, U.; Larsson, B.; Tuve, S.; Wehner, R.; Zimmermann, N.; et al. (18 authors)
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Haematologica -The Hematology Journal 99(2014), e86-e89
DOI: 10.3324/haematol.2013.101071
ISSN: 1592-8721
Combined measurement of tumor perfusion and glucose metabolism for improved tumor characterization in advanced cervical carcinoma: A PET/CT pilot study using [15O]water and [18F]fluorodeoxyglucose
Apostolova, I.; Hofheinz, F.; Buchert, R.; Steffen, I. G.; Michel, R.; et al. (11 authors)
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Strahlentherapie und Onkologie 190(2014), 575-581
DOI: 10.1007/s00066-014-0611-7
ISSN: 1439-099X
Effect of [18F]FMISO stratified dose-escalation on local control in FaDu hSCC in nude mice
Schütze, C.; Bergmann, R.; Brüchner, K.; Mosch, B.; Yaromira, A.; et al. (13 authors)
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Radiotherapy and Oncology 111(2014), 81-87
DOI: 10.1016/j.radonc.2014.02.005
ISSN: 1879-0887
Potential of a Cetuximab-based radioimmunotherapy combined with external irradiation manifests in a 3-D cell assay
Ingargiola, M.; Runge, R.; Heldt, J.-M.; Freudenberg, R.; Steinbach, J.; et al. (10 authors)
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International Journal of Cancer 135(2014), 968-980
DOI: 10.1002/ijc.28735
ISSN: 1097-0215
Evaluation and automatic correction of metal-implant-induced artifacts in MR-based attenuation correction in whole-body PET/MR imaging
Schramm, G.; Maus, J.; Hofheinz, F.; Petr, J.; Lougovski, A.; et al. (8 authors)
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Physics in Medicine and Biology 59(2014), 2713-2726
DOI: 10.1088/0031-9155/59/11/2713
ISSN: 0031-9155
EGF receptor-targeting peptide conjugate incorporating a near-IR fluorescent dye and a novel 1,4,7-triazacyclononane-based 64Cu(II) chelator assembled via click chemistry
Viehweger, K.; Barbaro, L.; Pombo García, K.; Joshi, T.; Geipel, G.; et al. (9 authors)
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Bioconjugate Chemistry 25(2014)5, 1011-1022
DOI: 10.1021/bc5001388
Diagnostic nanoparticle targeting of the EGF-receptor in complex biological conditions using single-domain antibodies
Zarschler, K.; Prapainop, K.; Mahon, E.; Rocks, L.; Bramini, M.; et al. (8 authors)
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Nanoscale 6(2014), 6046-6056
DOI: 10.1039/c4nr00595c
Early increase of cannabinoid receptor density after experimental traumatic brain injury in the newborn piglet
Donat, C. K.; Fischer, F.; Walter, B.; Deuther-Conrad, W.; Brodhun, M.; et al. (7 authors)
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Acta Neurobiologiae Experimentalis 74(2014), 197-210
ISSN: 0365-0820
Cytotoxic properties of radionuclide-conjugated Cetuximab without and in combination with external irradiation in head and neck cancer cells in vitro
Eke, I.; Ingargiola, M.; Förster, C.; Kunz-Schughart, L.; Baumann, M.; et al. (12 authors)
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International Journal of Radiation Biology 90(2014)8, 678-686
DOI: 10.3109/09553002.2014.899446
FDG PET/MR for lymph node staging in head and neck cancer
Platzek, I.; Beuthien-Baumann, B.; Schneider, M.; Gudziol, V.; Kitzler, H. H.; et al. (11 authors)
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European Journal of Radiology 83(2014)7, 1163-1168
DOI: 10.1016/j.ejrad.2014.03.023
Distinctive In Vivo Kinetics of the New Sigma1 Receptor Ligands (R)-(+) and (S)-(-)- 18F-Fluspidine in Porcine Brain
Brust, P.; Deuther-Conrad, W.; Becker, G.; Patt, M.; Dont, C. K.; et al. (15 authors)
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Journal of Nuclear Medicine 55(2014)10, 1730-1736
DOI: 10.2967/jnumed.114.137562
ISSN: 0161-5505
Correction of scan time dependence of standard uptake values in oncological PET
van den Hoff, J.; Lougovski, A.; Schramm, G.; Maus, J.; Oehme, L.; et al. (9 authors)
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EJNMMI Research 4(2014), 18
DOI: 10.1186/2191-219X-4-18
Combined PET/MR: Where Are We Now? Summary Report of the Second International Workshop on PET/MR Imaging April 8–12, 2013, Tubingen, Germany
Bailey, D. L.; Barthel, H.; Beuthien-Baumann, B.; Beyer, T.; Bisdas, S.; et al. (29 authors)
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Molecular Imaging and Biology 16(2014)3, 295-310
DOI: 10.1007/s11307-014-0725-4
ISSN: 1536-1632
Metastatic potential of B16-F10 melanoma cells is enhanced by extracellular S100A4 derived from RAW264.7 macrophages
Haase-Kohn, C.; Wolf, S.; Herwig, N.; Mosch, B.; Pietzsch, J.
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Biochemical and Biophysical Research Communications 446(2014), 143-148
DOI: 10.1016/j.bbrc.2014.02.126
Simultaneous Targeting of Prostate Stem Cell Antigen and Prostate-Specific Membrane Antigen Improves the Killing of Prostate Cancer Cells Using a Novel Modular T Cell-Retargeting System
Arndt, C.; Feldmann, A.; Koristka, S.; Cartellieri, M.; Dimmel, M.; et al. (8 authors)
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The Prostate 74(2014), 1335-1346
DOI: 10.1002/pros.22850
A novel ex vivo Isolation and Expansion Procedure for Chimeric Antigen Receptor Engrafted Human T Cells
Cartellieri, M.; Koristka, S.; Arndt, C.; Feldmann, A.; Stamova, S.; et al. (15 authors)
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PLOS ONE 9(2014)4, e93745
DOI: 10.1371/journal.pone.0093745
Characterization of a novel single-chain bispecific antibody for retargeting of T cells to tumor cells via the TCR co-receptor CD8
Michalk, I.; Feldmann, A.; Koristka, S.; Arndt, C.; Cartellieri, M.; et al. (8 authors)
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PLOS ONE 9(2014)4, e95517
DOI: 10.1371/journal.pone.0095517
Letter to the editor: Cytotoxic response of human regulatory 1 T cells upon T cell receptor-mediated activation – a 2 matter of purity
Koristka, S.; Cartellieri, M.; Arndt, C.; Feldmann, A.; Töpfer, K.; et al. (9 authors)
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Blood Cancer Journal 4(2014), e199
DOI: 10.1038/bcj.2014.20
Visualizing inflammation activity in rheumatoid arthritis with Tc-99 m Anti-CD4-mAb fragment scintigraphy
Steinhoff, K.; Pierer, M.; Siegert, J.; Pigla, U.; Laub, R.; et al. (15 authors)
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Nuclear Medicine and Biology 41(2014), 350-354
DOI: 10.1016/j.nucmedbio.2013.12.018
Influence of different chelators on the radiochemical properties of a 68-Gallium labelled bombesin analogue.
Asti, M.; Iori, M.; Capponi, P. C.; Atti, G.; Rubagotti, S.; et al. (11 authors)
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Nuclear Medicine and Biology 41(2014), 24-35
DOI: 10.1016/j.nucmedbio.2013.08.010
Radiolabeled anti-EGFR-antibody improves local tumor control after external beam radiotherapy and offers theragnostic potential
Koi, L.; Bergmann, R.; Brüchner, K.; Pietzsch, J.; Pietzsch, H.-J.; et al. (9 authors)
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Radiotherapy and Oncology 110(2014), 362-369
DOI: 10.1016/j.radonc.2013.12.001
Establishment of two complementary in vitro assays for radiocopper complexes achieving reliable and comparable evaluation of in vivo stability
Zarschler, K.; Kubeil, M.; Stephan, H.
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RSC Advances 4(2014), 10157-10164
DOI: 10.1039/c3ra47302c
TCR/CD3 activation and co-stimulation combined in one T cell retargeting system improve anti-tumor immunity
Cartellieri, M.; Arndt, C.; Feldmann, A.; von Bonin, M.; Ewen, E.-M.; et al. (14 authors)
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OncoImmunology 2(2014)12, e26770
DOI: 10.4161/onci.26770
Evaluation of PET quantification accuracy in vivo - Comparison of measured FDG concentration in the bladder with urine samples / In-vivo-Evaluation der Quantifizierungsgenauigkeit der PET - Vergleich der gemessenen FDG-Konzentration in der Blase mit Urinproben
Maus, J.; Hofheinz, F.; Schramm, G.; Oehme, L.; Beuthien-Baumann, B.; et al. (10 authors)
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Nuklearmedizin 53(2014), 67-77
DOI: 10.3413/Nukmed-0588-13-05
Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: Description of a novel modular targeting system
Arndt, C.; Feldmann, A.; von Bonin, M.; Cartellieri, M.; Ewen, E.-M.; et al. (14 authors)
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Leukemia 28(2014), 59-69
DOI: 10.1038/leu.2013.243
ISSN: 0887-6924
Asymmetric Synthesis of Spirocyclic 2-Benzopyrans for Positron Emission Tomography of σ1 Receptors in the Brain
Holl, K.; Schepmann, D.; Fischer, S.; Ludwig, F. A.; Hiller, A.; et al. (9 authors)
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Pharmaceuticals 7(2014), 78-112
DOI: 10.3390/ph7010078
ISSN: 1424-8247
A volume of intersection approach for on-the-fly system matrix calculation in 3D PET image reconstruction
Lougovski, A.; Hofheinz, F.; Langner, J.; Schramm, G.; Will, E.; et al. (6 authors)
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Physics in Medicine and Biology 59(2014)3, 561-577
DOI: 10.1088/0031-9155/59/3/561
Synthesis and biological evaluation of both enantiomers of [18F]flubatine, promising radiotracers with fas kinetics for the imaging of α4β2-nicotinic acetylcholine receptors
Smits, R.; Fischer, S.; Hiller, A.; Deuther-Conrad, W.; Wenzel, B.; et al. (11 authors)
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Bioorganic & Medicinal Chemistry 22(2014), 804-812
DOI: 10.1016/j.bmc.2013.12.011
Development of 18F-labeled radiotracers for neuroreceptor imaging with positron emission tomography
Brust, P.; van den Hoff, J.; Steinbach, J.
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Neuroscience Bulletin 30(2014)5, 777-811
DOI: 10.1007/s12264-014-1460-6
ISSN: 1995-8218
Radiolabeled cetuximab conjugates for EGFR targeted cancer diagnostics and therapy
Sihver, W.; Pietzsch, J.; Krause, M.; Baumann, M.; Steinbach, J.; et al. (6 authors)
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Pharmaceuticals 7(2014)3, 311-338
DOI: 10.3390/ph7030311
Performance Evaluation of Stationary and Semi-Stationary Acquisition with a Non-Stationary Small Animal Multi-Pinhole SPECT System
Lange, C.; Apostolova, I.; Lukas, M.; Huang, K. P.; Hofheinz, F.; et al. (8 authors)
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Molecular Imaging and Biology 16(2014)3, 311-316
Online First (2013) DOI: 10.1007/s11307-013-0702-3
Hydroxyalkylation with Cyclic Sulfates: Synthesis of Carbazole Derived CB2 Ligands with Increased Polarity
Lueg, C.; Galla, F.; Frehland, B.; Schepmann, D.; Daniliuc, C. G.; et al. (8 authors)
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Archiv der Pharmazie 347(2014), 21-31
DOI: 10.1002/ardp.201300255
Automation of the radiosynthesis and purification procedures for [18F]Fluspidine preparation, a new radiotracer for clinical investigations in PET imaging of σ1 receptors in brain.
Maisonial-Besset, A.; Funke, U.; Wenzel, B.; Fischer, S.; Holl, K.; et al. (8 authors)
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Applied Radiation and Isotopes 84(2014), 1-7
DOI: 10.1016/j.apradiso.2013.10.015
Molecular Imaging of σ1 Receptors In Vivo: Current Status and Perspectives
Brust, P.; Deuther-Conrad, W.; Lehmkuhl, K.; Jia, H.; Wünsch, B.
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Current Medicinal Chemistry 21(2014)1, 35-69
DOI: 10.2174/09298673113209990214
Modeling Magnetization Transfer Effects of Q2TIPS Bolus Saturation in Multi-TI Pulsed Arterial Spin Labeling
Petr, J.; Schramm, G.; Hofheinz, F.; Langner, J.; van den Hoff, J.
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Magnetic Resonance in Medicine 72(2014), 1007-1014
Online First (2013) DOI: 10.1002/mrm.25011
Establishment of a small animal tumour model for in vivo studies with low energy laser accelerated particles
Brüchner, K.; Beyreuther, E.; Baumann, M.; Krause, M.; Oppelt, M.; et al. (6 authors)
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Radiation Oncology 9(2014), 57
DOI: 10.1186/1748-717X-9-57
Fluorine containing 6,7-dialkoxybiaryl-based inhibitors for phosphodiesterase 10A: Synthesis and in vitro evaluation of inhibition potency, selectivity and metabolism
Schwan, G.; Asskar, G. B.; Höfgen, N.; Kubicova, L.; Funke, U.; et al. (12 authors)
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ChemMedChem 9(2014)7, 1476-1487
DOI: 10.1002/cmdc.201300522
ISSN: 1860-7187
Template-based approach for detecting motor task activation-related hyperperfusion in pulsed ASL data
Petr, J.; Ferré, J.-C.; Raoult, H.; Bannier, E.; Gauvrit, J.-Y.; et al. (6 authors)
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Human Brain Mapping 35(2014)4, 1179-1189
Online First (2013) DOI: 10.1002/hbm.22243
Production of 85Sr at a 18 MeV-cyclotron and purification for geochemical investigations
Mansel, A.; Gruhne, S.; Franke, K.; Fischer, S.
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Applied Radiation and Isotopes 92(2014), 22-24
DOI: 10.1016/j.apradiso.2014.06.001
How plants cope with heavy metals
Viehweger, K.
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Botanical Studies 55(2014), 35
DOI: 10.1186/1999-3110-55-35
ISSN: 1817-406X
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