Practical trainings, student assistants and theses
Offer | School practical training | Master theses | Research Assistant | Holiday job | Student practical training | Volunteer internship | Diploma theses | Bachelor theses | Student Assistant | Compulsory internship | |
---|---|
Institute/ Dep. | All | FKVF | FWDF | FWDF-P | FWDF-V | FWGP-G | | FWGT-B | FWIO-N | FWIO-T | FWIZ | FWKE | FWPC | FWU |
Formatting | Table | |
Development of Biomolecules for Selective Binding of Specific Short PFAS (Id 436)
Bachelor theses / Master theses / Diploma theses / Compulsory internship / Volunteer internship
The research project focuses on identifying biomolecules for the selective binding of short per- and polyfluoroalkyl substances (PFAS). The aim is to develop biomolecules for the targeted removal of short PFAS from aqueous solutions such as industrial wastewater. Using advanced screening methods, biomolecules or microorganisms that can interact with specific groups of short-chain PFAS compounds will be identified. Tasks include extensive literature research on relevant PFAS molecules and potential biomolecule ligands, method development for characterizing interactions and screening available biomolecules and microbes.
Department: Biotechnology
Contact: Dr. Kutschke, Sabine, Dr. Lederer, Franziska, Dr. Pollmann, Katrin
Requirements
- Studies in biotechnology, chemistry, environmental sciences, biochemistry, or a comparable field
- Interest in practical, interdisciplinary research
- Knowledge of fundamental biochemical and molecular biology principles and techniques
- Careful and independent working style
Conditions
- Work in an interdisciplinary and international team
- Working place language is English
- Duration of the internship or thesis according to the study regulations
- Starting date is flexible
Online application
Please apply online: english / german
Mutation and Enrichment Studies in the Context of Directed Evolution using Multiple Phage Display Experiments (Id 417)
Master theses / Diploma theses / Compulsory internship
The application of phage surface display (PSD) technology has accelerated developments in the field of biomolecular sensors and materials science. A practical complement to this technology is Next-Generation Sequencing (NGS). In this combination, a more comprehensive view of biopanning rounds with a deep insight into the entire sequence space is made possible. It is possible to identify sequencing artefacts, determine sequence number and structure, recognize binding motifs and observe the evolution of the phage library over the course of an experiment. PSD in combination with biopanning is able to select candidates with high affinity and selectivity to the desired substrates from large peptide libraries. In practice, this specific enrichment of peptides leads to a reduction in library diversity. It should therefore be possible to better visualize this reduction in sequence space using data clustering methods in order to better understand distances between similar sequence families.
Department: BioKollekt
Contact: Bloß, Christoph
Requirements
Prerequisite is a valid enrollment in a Master's program in bioinformatics, biotechnology, molecular biology, biochemistry, biology or a related natural science program. Furthermore:
- Interest in data cluster methods and bioinformatics
- Basic knowledge in bioinformatics, statistics, stochastics and clustering
- Experience with a programming language (e.g. Python, R, C, C++ or other)
- Ability to work independently and in a team
Interested students are invited to submit their application documents including CV, last academic transcript and letter of motivation.
Conditions
The topic is to be worked on as part of a Master's thesis in conjunction with a mandatory internship. This results in a duration of 12 months. The duration can be extended or adjusted in consultation with the supervisor. We can offer you:
- An innovative multidisciplinary research environment related to relevant issues in resource technology
- Supervision by experienced scientists and researchers
- Practical experience in the field of bioinformatics and directed evolution