Publications of Institute of Radiopharmaceutical Cancer Research - Year 2020

87 Publications

2020

Preparation of 5‑[131I]iodotubercidin for the detection of adenosine kinase

Bier, D.; Holschbah, M.; Wedekind, F.; Sihver, W.; Drewes, B.; et al. (9 authors)

Telemedicine pre and post COVID-19: Lessons for commercialization based on previous use cases

Ferenczi, G. L.; Mahmood, A.; Bergmann, R.

  • Open Access Logo Journal of the International Society for Telemedicine and eHealth 8(2020), e8
    DOI: 10.29086/JISfTeH.8.e8

Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice

Thomas, M. J.; Major, E.; Benedek, A.; Horvath, I.; Mathe, D.; et al. (9 authors)

Nanosensor-Based Real-Time Monitoring of Stress Biomarkers in Human Saliva Using a Portable Measurement System

Klinghammer, S.; Voitsekhivska, T.; Licciardello, N.; Kim, K.; Baek, C.-K.; et al. (10 authors)

PET measured hypoxia and MRI parameters in re-irradiated head and neck squamous cell carcinomas: findings of a prospective pilot study

Rogasch, J.; Beck, M.; Stromberger, C.; Hofheinz, F.; Ghadjar, P.; et al. (12 authors)

68Ga, 44Sc and 177Lu-labeled AAZTA5-PSMA-617: synthesis, radiolabeling, stability and cell binding compared to DOTA-PSMA-617 analogues

Sinnes, J.; Bauder-Wüst, U.; Schäfer, M.; Moon, E.; Kopka, K.; et al. (6 authors)

Comparative Studies of Light-Responsive Swimmers: Janus Nanorods versus Spherical Particles

Eichler-Volf, A.; Huang, T.; Vazquez Luna, F.; Alsaadawi, Y.; Stierle, S.; et al. (9 authors)

KRAS mutation effects on the 2-[18F]FDG PET uptake of colorectal adenocarcinoma metastases in the liver

Popovic, M.; Talarico, O.; van den Hoff, J.; Kunin, H.; Zhang, Z.; et al. (11 authors)

Short-duration dynamic FDG PET imaging: Optimization and clinical application

Samimi, R.; Kamali-Asl, A.; Geramifar, P.; van den Hoff, J.; Rahmim, A.

Asphericity of tumor FDG uptake in non-small cell lung cancer: Reproducibility and implications for harmonization in multicenter studies

Rogasch, J.; Furth, C.; Bluemel, S.; Radojewski, P.; Amthauer, H.; et al. (6 authors)

A FDG-PET radiomics signature detects esophageal squamous cell carcinoma patients who do not benefit from chemoradiation

Li, Y.; Beck, M.; Päßler, T.; Lili, C.; Wu, H.; et al. (17 authors)

Nanocytometer for smart analysis of peripheral blood and acute myeloid leukemia: a pilot study

Schütt, J.; Sandoval Bojorquez, D. I.; Avitabile, E.; Oliveros Mata, E. S.; Milyukov, G.; et al. (17 authors)

The pyrazolo[3,4-d]pyrimidine-based kinase inhibitor NVP-BHG712: Effects of regioisomers on tumor growth, perfusion, and hypoxia in EphB4-positive A375 melanoma xenografts

Neuber, C.; Tröster, A.; Löser, R.; Belter, B.; Schwalbe, H.; et al. (6 authors)

Electrochemical detection of ascorbic acid in artificial sweat using a flexible alginate/CuO-modified electrode

Ibarlucea, B.; Pérez, R. A.; Belyaev, D.; Baraban, L.; Cuniberti, G.

Development of PSMA-1007 - Related Series of 18F-Labeled Glu-ureido type PSMA inhibitors.

Cardinale, J.; Roscher, M.; Schaefer, M.; Geerlings, M.; Benešová, M.; et al. (13 authors)

Three-dimensional cell culture systems in radiopharmaceutical cancer research

Doctor, A.; Seifert, V.; Ullrich, M.; Hauser, S.; Pietzsch, J.

Prognostic value of baseline [18F]-fluorodeoxyglucose positron emission tomography parameters MTV, TLG and asphericity in an international multicenter cohort of nasopharyngeal carcinoma patients

Zschaeck, S.; Li, Y.; Lin, Q.; Beck, M.; Amthauer, H.; et al. (16 authors)

Applying tissue slice culture in cancer research—insights from preclinical proton radiotherapy

Suckert, T.; Rassamegevanon, T.; Müller, J.; Dietrich, A.; Graja, A.; et al. (10 authors)

In silico finding of key interaction mediated α3β4 and α7 nicotinic acetylcholine receptor ligand selectivity of quinuclidine-triazole chemotype

Arunrungvichian, K.; Chongruchiroj, S.; Sarasamkan, J.; Schüürmann, G.; Brust, P.; et al. (6 authors)

Live-cell Imaging with Aspergillus Fumigatus-specific fluorescent Siderophore Conjugates

Pfister, J.; Lichius, A.; Summer, D.; Haas, H.; Kanagasundaram, T.; et al. (7 authors)

HIF2α supports pro-metastatic behavior in pheochromocytomas/paragangliomas

Bechmann, N.; Moskopp, M. L.; Ullrich, M.; Calsina, B.; Wallace, P. W.; et al. (23 authors)

Adenosine/A2B Receptor Signaling Ameliorates the Effects of Aging and Counteracts Obesity

Gnad, T.; Navarro, G.; Lahesmaa, M.; Reverte-Salisa, L.; Copperi, F.; et al. (31 authors)

Rapidly Switchable Universal CAR-T Cells for Treatment of CD123-Positive Leukemia

Loff, S.; Dietrich, J.; Meyer, J.-E.; Riewaldt, J.; Spehr, J.; et al. (14 authors)

Development and In Vivo Application of a Water-Soluble Anticancer Copper Ionophore System Using a Temperature-Sensitive Liposome Formulation

Gaál, A.; Garay, T. M.; Horváth, I.; Máthé, D.; Szöllösi, D.; et al. (15 authors)

Inverse Solidification Induced by Active Janus Particles

Huang, T.; Misko, V. R.; Gobeil, S.; Wang, X.; Nori, F.; et al. (10 authors)

Intrinsic plasticity of silicon nanowire neurotransistors for dynamic memory and learning functions

Baek, E.; Ranjan Das, N.; Vittorio Cannistraci, C.; Rim, T.; Cañón Bermúdez, G. S.; et al. (14 authors)

Nanosensors-Assisted Quantitative Analysis of Biochemical Processes in Droplets

Belyaev, D.; Schütt, J.; Ibarlucea, B.; Rim, T.; Baraban, L.; et al. (6 authors)

Synthesis, characterization and evaluation of 68Ga labelled monomeric and dimeric quinazoline derivatives of the HBED-CC chelator targeting the epidermal growth factor receptor

Liolios, C.; Shegani, A.; Roupa, I.; Kiritsis, C.; Makarem, A.; et al. (11 authors)

Versatile chimeric antigen receptor platform for controllable and combinatorial T cell therapy

Feldmann, A.; Hoffmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; et al. (13 authors)

Combined tumor plus nontumor interim FDG‐PET parameters are prognostic for response to chemoradiation in squamous cell esophageal cancer

Zschaeck, S.; Li, Y.; Bütof, R.; Lili, C.; Hua, W.; et al. (15 authors)

Reconstructed spatial resolution and contrast recovery with Bayesian penalized likelihood reconstruction (Q.Clear) for FDG-PET compared to time-of-flight (TOF) with point spread function (PSF)

Rogasch, J.; Suleiman, S.; Hofheinz, F.; Bluemel, S.; Lukas, M.; et al. (7 authors)

Olfactory dysfunction correlates with putaminal dopamine turnover in early de novo Parkinson’s disease

Löhle, M.; Wolz, M.; Beuthien-Baumann, B.; Oehme, L.; van den Hoff, J.; et al. (8 authors)

The influence of different artificial extracellular matrix implant coatings on the regeneration of a critical size femur defect in rats

Förster, Y.; Schulze, S.; Penk, A.; Neuber, C.; Möller, S.; et al. (11 authors)

Recent insights in barium-131 as a diagnostic match for radium-223: cyclotron production, separation, labeling and imaging

Reissig, F.; Bauer, D.; Ullrich, M.; Kreller, M.; Pietzsch, J.; et al. (9 authors)

Metabolomics, machine learning and immunohistochemistry to predict succinate dehydrogenase mutational status in phaeochromocytomas and paragangliomas

Wallace, P. W.; Conrad, C.; Brückmann, S.; Pang, Y.; Caleiras, E.; et al. (26 authors)

Deuteration versus ethylation – strategies to improve the metabolic fate of a 18F-labeled celecoxib derivative

Laube, M.; Gassner, C.; Neuber, C.; Wodtke, R.; Ullrich, M.; et al. (12 authors)

A radiopharmacologist's and radiochemist's view on targeting the Eph/ephrin receptor tyrosine kinase system

Neuber, C.; Belter, B.; Mamat, C.; Pietzsch, J.

Individual patient data meta-analysis of FMISO and FAZA hypoxia PET scans from head and neck cancer patients undergoing definitive radio-chemotherapy

Zschaeck, S.; Löck, S.; Hofheinz, F.; Zips, D.; Mortensen, L.; et al. (17 authors)

Dose dependent cerebellar atrophy in glioma patients after radio(chemo)therapy

Raschke, F.; Seidlitz, A.; Wesemann, T.; Löck, S.; Jentsch, C.; et al. (14 authors)

Automated [18F]PSMA-1007 production by a single use cassette-type synthesizer for clinical examination

Naka, S.; Watabe, T.; Kurimoto, K.; Uemura, M.; Soeda, F.; et al. (14 authors)

Light-Activated Carbon Monoxide Prodrugs Based on Bipyridyl Dicarbonyl Ruthenium(II) Complexes

Geri, S.; Krunclova, T.; Janouskova, O.; Panek, J.; Hruby, M.; et al. (11 authors)

Adaptor CAR platforms - next generation of T cell-based cancer immunotherapy

Arndt, C.; Fasslrinner, F.; Loureiro, L. R.; Koristka, S.; Feldmann, A.; et al. (6 authors)

Surface Modification of Silicon Nanowire Based Field Effect Transistors with Stimuli Responsive Polymer Brushes for Biosensing Applications

Klinghammer, S.; Rauch, S.; Pregl, S.; Uhlmann, P.; Baraban, L.; et al. (6 authors)

Two‐Dimensional Boronate Ester Covalent Organic Framework Thin Films with Large Single Crystalline Domains for Neuromorphic Memory Device

Park, S.; Liao, Z.; Ibarlucea, B.; Qi, H.; Lin, H.-H.; et al. (19 authors)

Anisotropic exclusion effect between photocatalytic Ag/AgCl Janus particles and passive beads in a dense colloidal matrix

Huang, T.; Gobeil, S.; Wang, X.; Misko, V.; Nori, F.; et al. (10 authors)

Highly efficient targeting of EGFR-expressing tumor cells with UniCAR T cells via target modules based on Cetuximab®

Jureczek, J.; Feldmann, A.; Bergmann, R.; Arndt, C.; Berndt, N.; et al. (12 authors)

Extended half-life target module for sustainable UniCAR T-cell treatment of STn-expressing cancers

Loureiro, L. R.; Feldmann, A.; Bergmann, R.; Koristka, S.; Berndt, N.; et al. (11 authors)

Sigma-1 Receptor Positron Emission Tomography: A New Molecular Imaging Approach Using ( S)-(-)-[ 18 F]Fluspidine in Glioblastoma

Toussaint, M.; Deuther-Conrad, W.; Kranz, M.; Fischer, S.; Ludwig, F.-A.; et al. (11 authors)

Synthesis and evaluation of new 1-oxa-8-azaspiro[4.5]decane derivatives as candidate radioligands for sigma-1 receptors

Tian, J.; He, Y.; Deuther-Conrad, W.; Fu, H.; Xie, F.; et al. (12 authors)

Adjuvant drug-assisted bone healing: advances and challenges in drug delivery approaches

Rothe, R.; Hauser, S.; Neuber, C.; Laube, M.; Schulze, S.; et al. (7 authors)

Development of a radiofluorinated adenosine A2B receptor antagonist as potential ligand for PET imaging

Lindemann, M.; Moldovan, R.-P.; Hinz, S.; Deuther-Conrad, W.; Gündel, D.; et al. (13 authors)

Cation exchange protocols to radiolabel aqueous stabilized ZnS, ZnSe and CuFeS2 nanocrystals with 64Cu for dual radio- and photo-thermal therapy

Avellini, T.; Soni, N.; Silvestri, N.; Fiorito, S.; de Donato, F.; et al. (12 authors)

Development of novel analogs of the monocarboxylate transporter ligand FACH and biological validation of one potential radiotracer for PET imaging

Sadeghzadeh, M.; Wenzel, B.; Gündel, D.; Deuther-Conrad, W.; Toussaint, M.; et al. (13 authors)

Preclinical incorporation dosimetry of [18F]FACH - a novel 18F-labeled MCT1/MCT4 lactate transporter inhibitor for imaging cancer metabolism with PET

Sattler, B.; Kranz, M.; Wenzel, B.; Thachaantara Jain, N.; Moldovan, R.-P.; et al. (13 authors)

Rhenium and technetium-complexed silicon rhodamines as near-infrared imaging probes for bimodal SPECT- and optical imaging

Kanagasundaram, T.; Kramer, C. S.; Boros, E.; Kopka, K.

UniCAR T cell immunotherapy enables efficient elimination of radioresistant cancer cells

Arndt, C.; Loureiro, L. R.; Feldmann, A.; Jureczek, J.; Bergmann, R.; et al. (22 authors)

Contemporary Synthesis of Ultrasmall (sub-10 nm) Upconverting Nanomaterials

Joshi, T.; Mamat, C.; Stephan, H.

Rapid Thermodynamically Stable Complex Formation of [nat/111In]In3+, [nat/90Y]Y3+, and [nat/177Lu]Lu3+ with H6dappa

Kostelnik, T.; Xiaozhu, W.; Southcott, L. D.; Wagner, H.; Kubeil, M.; et al. (8 authors)

Chelation in One Fell Swoop: Optimizing Ligands for Smaller Radiometal Ions

Choudhary, N.; Jaraquemada-Pelaez, M.; Zarschler, K.; Wang, X.; Radchenko, V.; et al. (8 authors)

Accurate MR image registration to anatomical reference space for diffuse glioma

Visser, M.; Petr, J.; Müller, D. M.; Eijgelaar, R. S.; Hendriks, E. J.; et al. (12 authors)

Recombinant expression of ecto-nucleotide pyrophosphatase/phosphodiesterase 4 (NPP4) and development of a luminescence-based assay to identify inhibitors

Lopez, V.; Lee, S.-Y.; Stephan, H.; Müller, C. E.

Synthesis, radiolabeling and first biological characterization of 18F-labeled xanthine derivatives for PET imaging of Eph receptors

Pretze, M.; Neuber, C.; Kinski, E.; Belter, B.; Köckerling, M.; et al. (9 authors)

Regulation of bone regeneration

Jung, F.; Pietzsch, J.

  • Open Access Logo Clinical Hemorheology and Microcirculation 73(2020)3, 379-380
    DOI: 10.3233/CH-199101
    ISSN: 1386-0291

Carboranyl Derivatives of Rofecoxib with Cytostatic Activity Against Human Melanoma and Colon Cancer Cells

Buzharevski, A.; Paskas, S.; Sárosi, M.-B.; Laube, M.; Lönnecke, P.; et al. (11 authors)

The sigma-1 receptor: potential role in the modulation of cellular radiation sensitivity

Belter, B.; Deuther-Conrad, W.; Hofheinz, F.; Bachmann, M.; Brust, P.; et al. (6 authors)

“UniCAR”-modified off-the-shelf NK-92 cells for targeting of GD2-expressing tumour cells

Mitwasi, N.; Feldmann, A.; Arndt, C.; Koristka, S.; Berndt, N.; et al. (24 authors)

Interprofessionelle Kooperation in klinischen Studien. Zunehmender Bedarf, Komplexität und Anregungen am Beispiel einer prospektiv-onkologischen Multicenter-Studie.

Zippel, C.; Giesel, F.; Kopka, K.

Sub-10 nm Radiolabeled Barium Sulfate Nanoparticles as Carriers for Theranostic Applications and Targeted Alpha Therapy

Reissig, F.; Zarschler, K.; Hübner, R.; Pietzsch, H.-J.; Kopka, K.; et al. (6 authors)

Current status of PSMA-radiotracers for prostate cancer: data analysis of prospective trials listed on ClinicalTrials.gov

Zippel, C.; Ronski, S. C.; Bohnet-Joschko, S.; Giesel, F. L.; Kopka, K.

Radioimmunotherapy in Combination with Reduced-Intensity Conditioning for Allogeneic Hematopoietic Cell Transplantation in Patients with Advanced Multiple Myeloma

Fasslrinner, F.; Stölzel, F.; Kramer, M.; Teipel, R.; Brogsitter, C.; et al. (13 authors)

Cerebral Oxygen Metabolism in Adults with Sickle Cell Disease

Václavů, L.; Petr, J.; Petersen, E. T.; Mutsaerts, H. J. M. M.; Majoie, C. B. L.; et al. (9 authors)

Solution-Phase Synthesis of the Fluorogenic TGase 2 Acyl Donor Z-Glu(HMC)-Gly-OH and its Use for Inhibitor and Amine Substrate Characterisation

Wodtke, R.; Pietsch, M.; Löser, R.

Newly synthesized fluorinated cinnamylpiperazines possessing low in vitro MAO-B binding

Jevtić, I. I.; Lai, T. H.; Penjišević, J. Z.; Dukic-Stefanovic, S.; Andrić, D. B.; et al. (8 authors)

Active Targeting of Dendritic Polyglycerols for Diagnostic Cancer Imaging

Kritee, P.; Neuber, C.; Zarschler, K.; Wodtke, J.; Meister, S.; et al. (8 authors)

PET Imaging of the Adenosine A2A Receptor in the Rotenone-Based Mouse Model of Parkinson’s Disease with [18F]FESCH Synthesized by a Simplified Two-Step One-Pot Radiolabeling Strategy

Schröder, S.; Lai, T. H.; Toussaint, M.; Kranz, M.; Chovsepian, A.; et al. (13 authors)

Inhibition of ATP hydrolysis restores airway surface liquid production in cystic fibrosis airway epithelia

van Heusden, C.; Button, B.; Anderson, W. H.; Ceppe, A.; Morton, L. C.; et al. (12 authors)

ExploreASL: an image processing pipeline for multi-center ASL perfusion MRI studies

Mutsaerts, H. J.; Petr, J.; Groot, P. F.; Vandemaele, P.; Ingala, S.; et al. (42 authors)

Validation of an independent prognostic value of the asphericity of F18-fluorodeoxyglucose (FDG) uptake in non-small cell lung cancer (NSCLC) patients undergoing treatment in curative intent

Rogasch, J.; Furth, C.; Chibolela, C.; Hofheinz, F.; Ochsenreither, S.; et al. (11 authors)

The effect of hypoxia on the induction of strand breaks in plasmid DNA by alpha-, beta- and Auger electron-emitters 223Ra, 188Re, 99mTc and DNA-binding 99mTc-pyrene

Reissig, F.; Wunderlich, G.; Runge, R.; Freudenberg, R.; Lühr, A.; et al. (6 authors)

Versatile Bispidine-based Bifunctional Chelators for 64CuII-Labelling of Biomolecules

Singh, G.; Zarschler, K.; Hunoldt, S.; Santana Martinez, I. I.; Rühl, C.; et al. (12 authors)

Ultrasmall silicon nanoparticles as a promising platform for multimodal imaging

Singh, G.; Ddungu, J. L. Z.; Licciardello, N.; Bergmann, R.; de Cola, L.; et al. (6 authors)

Multi-modality bedding platform for combined imaging and irradiation of mice

Müller, J.; Schürer, M.; Neubert, C.; Tillner, F.; Beyreuther, E.; et al. (12 authors)

Spatial Coefficient of Variation of Arterial Spin Labeling MRI as a Cerebrovascular Correlate of Carotid Occlusive Disease

Mutsaerts, H. J. M. M.; Petr, J.; Bokkers, R. P. H.; Lazar, R. M.; Marshall, R. S.; et al. (6 authors)

Synthesis and Characterization of an Epidermal Growth Factor Receptor selective Ru(II) Polypyridyl-Nanobody Conjugate as a Photosensitizer for Photodynamic Therapy

Karges, J.; Jakubaszek, M.; Mari, C.; Zarschler, K.; Goud, B.; et al. (7 authors)

Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion

Ferro, D.; Mutsaerts, H.; Hilal, S.; Kuijf, H.; Petersen, E. T.; et al. (11 authors)

Formation of calix[4]arenes with acyloxycarboxylate functions

Bauer, D.; Stipurin, S.; Köckerling, M.; Mamat, C.

High-precision image-guided proton irradiation of mouse brain sub-volumes

Suckert, T.; Müller, J.; Beyreuther, E.; Bütof, R.; Dietrich, A.; et al. (12 authors)

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