Publications of Institute of Radiopharmaceutical Cancer Research - Year 2017

61 Publications

2017

Synthesis and Pharmacological Evaluation of Identified and Putative Metabolites of the A₁ Adenosine Receptor Antagonist 8-Cyclopentyl-3-(3-fluoropropyl)-1-propylxanthine (CPFPX)

Holschbach, M. H.; Bier, D.; Sihver, W.; Schulze, A.; Neumaier, B.

Quantification: there is more to worry about than good scanner hardware and reliable calibration

Kotzerke, J.; van den Hoff, J.

  • European Journal of Nuclear Medicine and Molecular Imaging 44(2017)12, 1955-1957
    DOI: 10.1007/s00259-017-3808-z
    ISSN: 1619-7089

Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

Mattei, D.; Ivanov, A.; Ferrai, C.; Jordan, P.; Guneykaya, D.; et al. (21 authors)

An orthotopic xenograft model for high-risk non-muscle invasive bladder cancer in mice: influence of mouse strain, tumor cell count, dwell time and bladder pretreatment

Huebner, D.; Rieger, C.; Bergmann, R.; Ullrich, M.; Meister, S.; et al. (13 authors)

Nitric oxide-releasing selective cyclooxygenase-2 inhibitors as promising radiosensitizers in melanoma cells in vitro

Bechmann, N.; Hauser, S.; Hofheinz, F.; Kniess, T.; Pietzsch, J.

  • Open Access Logo Annals of Radiation Therapy and Oncology 1(2017)2, 1010

Potential of asphericity as a novel diagnostic parameter in the evaluation of patients with Ga-68-PSMA-HBED-CC PET-positive prostate cancer lesions

Meissner, S.; Janssen, J.; Prasad, V.; Brenner, W.; Diederichs, G.; et al. (8 authors)

Exploratory investigation of PSCA-protein expression in primary breast cancer patients reveals a link to HER2/neu overexpression.

Link, T.; Kuithan, F.; Ehninger, A.; Kuhlmann, J. D.; Kramer, M.; et al. (13 authors)

Mass spectrometry-based identification of a naturally presented receptor tyrosine kinase-like orphan receptor 1-derived epitope recognized by CD8+ cytotoxic T cells

Heidenreich, F.; Rücker-Braun, E.; Walz, J. S.; Eugster, A.; Kühn, D.; et al. (22 authors)

Novel Radiolabeled Bisphosphonates for PET Diagnosis and Endoradiotherapy of Bone Metastases

Pfannkuchen, N.; Meckel, M.; Bergmann, R.; Bachmann, M.; Bal, C.; et al. (9 authors)

Biological characterization of novel nitroimidazole-peptide conjugates in vitro and in vivo.

Bergmann, R.; Splith, K.; Pietzsch, J.; Bachmann, M.; Neundorf, I.

Characterization of a switchable chimeric antigen receptor platform in a pre-clinical solid tumor model

Bejestani, E. P.; Cartellieri, M.; Bergmann, R.; Ehninger, A.; Loff, S.; et al. (17 authors)

Retargeting of UniCAR T cells with an in vivo synthesized target module directed against CD19 positive tumor cells

Bachmann, D.; Aliperta, R.; Bergmann, R.; Feldmann, A.; Koristka, S.; et al. (19 authors)

Preparation of 18F-labeled building blocks for peptide conjugation using the "minimalist" approach

Omrane, M. A.; Zlatopolskiy, B. D.; Urusova, E.; Mamat, C.; Feni, L.; et al. (7 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S261
    DOI: 10.1002/jlcr.3508

Evaluation of Ba/Ra Polyoxopalladates for Radiopharmaceutical Applications

Gott, M.; Yang, P.; Kortz, U.; Pietzsch, H.-J.; Steinbach, J.; et al. (6 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S559
    DOI: 10.1002/jlcr.3508

Novel Functionalized Calixarenes as Host Molecules for Complexation with Alkaline Earth Metals

Steinberg, J.; Gott, M.; Pietzsch, H.-J.; Steinbach, J.; Mamat, C.

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S488
    DOI: 10.1002/jlcr.3508

Detection of Auger Electron Induced Strand Breaks on Plasmid DNA Caused by Technetium-99m Labeled Pyrene Derivatives

Wunderlich, G.; Reissig, F.; Mamat, C.; Pietzsch, H.-J.; Kotzerke, J.; et al. (6 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)S1, S365
    DOI: 10.1002/jlcr.3508

Development of novel target modules for retargeting of UniCAR T cells to GD2 positive tumor cells

Mitwasi, N.; Feldmann, A.; Bergmann, R.; Berndt, N.; Arndt, C.; et al. (17 authors)

Synthesis and X-ray Crystal Structure of N’-Cyano-N,N’-dimethyl-4-nitrobenzohydrazide

Löser, R.; Pitzschler, R.; Köckerling, M.

Individualized risk assessment in neuroblastoma: does the tumoral metabolic activity on 123I-MIBG SPECT predict the outcome?

Rogasch, J.; Hundsdoerfer, P.; Furth, C.; Wedel, F.; Hofheinz, F.; et al. (11 authors)

Increased FDG uptake on late-treatment PET in non-tumour-affected oesophagus is prognostic for pathological complete response and disease recurrence in patients undergoing neoadjuvant radiochemotherapy

Zschaeck, S.; Hofheinz, F.; Zöphel, K.; Bütof, R.; Jentsch, C.; et al. (12 authors)

PET Imaging Evaluation of Four sigma1 Radiotracers in Nonhuman Primates

Baum, E.; Cai, Z.; Bois, F.; Holden, D.; Lin, S.-F.; et al. (16 authors)

1‑(4‑[18F]Fluorobenzyl)-4-[(tetrahydrofuran-2-yl)methyl]piperazine: A Novel Suitable Radioligand with Low Lipophilicity for Imaging σ1 Receptors in the Brain

He, Y.; Xie, F.; Ye, J.; Deuther-Conrad, W.; Cui, B.; et al. (12 authors)

18F-Labeled indole-based analogs as highly selective radioligands for imaging sigma-2 receptors in the brain

Wang, L.; Ye, J.; He, Y.; Deuther-Conrad, W.; Zhang, J.; et al. (11 authors)

99mTechnetium-based Small Molecule Radiopharmaceuticals and Radiotracers Targeting Inflammation and Infection

Kniess, T.; Laube, M.; Wüst, F.; Pietzsch, J.

Test-retest variability of lesion SUV and lesion SUR in 18F-FDG PET: an analysis of data from two prospective multicenter trials

Hofheinz, F.; Apostolova, I.; Oehme, L.; Kotzerke, J.; van den Hoff, J.

FDG PET/MR in initial staging of sarcoma: Initial experience and comparison with conventional imaging

Platzek, I.; Beuthien-Baumann, B.; Schramm, G.; Maus, J.; Laniado, M.; et al. (8 authors)

Studies of carbon monoxide release from ruthenium(II) bipyridine carbonyl complexes upon UV light exposure

Kubeil, M.; Vernooij, R. R.; Kubeil, C.; Wood, B. R.; Graham, B.; et al. (7 authors)

Expression of ecto-nucleoside triphosphate diphosphohydrolases-2 and -3 by the enteric nervous system impacts inflammation in experimental colitis and Crohn’s disease

Feldbrügge, L.; Moss, A. C.; Yee, E. U.; Csizmadia, E.; Mitsuhashi, S.; et al. (13 authors)

Synthesis and in vitro evaluation of 5-substituted benzovesamicol analogs containing N-substituted amides as potential positron emission tomography tracers for the vesicular acetylcholine transporter

Roslin, S.; de Rosa, M.; Deuther-Conrad, W.; Eriksson, J.; Odell, L. R.; et al. (8 authors)

Radiosynthesis of (S)-[18F]T1: The first PET radioligand for molecular imaging of α3β4 nicotinic acetylcholine receptors

Sarasamkan, J.; Fischer, S.; Deuther-Conrad, W.; Ludwig, F.-A.; Scheunemann, M.; et al. (8 authors)

Preparation of a novel radiotracer targeting the EphB4 receptor via radiofluorination using spiro azetidinium salts as precursor

Wiemer, J.; Steinbach, J.; Pietzsch, J.; Mamat, C.

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017), 489-498
    DOI: 10.1002/jlcr.3526

Surface charge and particle size determine the metabolic fate of dendritic polyglycerols

Pant, K.; Pufe, J.; Zarschler, K.; Bergmann, R.; Steinbach, J.; et al. (9 authors)

A novel nanobody-based target module for retargeting of T lymphocytes to EGFR-expressing cancer cells via the modular UniCAR platform

Albert, S.; Arndt, C.; Feldmann, A.; Bergmann, R.; Bachmann, D.; et al. (18 authors)

A novel tumor pretargeting system based on complementary L-configured oligonucleotides

Schubert, M.; Bergmann, R.; Förster, C.; Sihver, W.; Vonhoff, S.; et al. (12 authors)

X-ray Structures of Succinimidyl Halobenzoates

Mamat, C.; Weiss, D.-H.; Köckerling, M.

Zwitterionic Modification of Ultra-Small Iron Oxide Nanoparticles for Reduced Protein Corona Formation

Pombo-Garcia, K.; Rühl, C.; Lam, R.; Ang, C.-S.; Scammells, P. J.; et al. (10 authors)

Do spiroindolines have the potential to replace vesamicol as lead compound for the development of radioligands targeting the vesicular acetylcholine transporter?

Lindemann, M.; Deuther-Conrad, W.; Moldovan, R.; Sekhar, K. V. G. C.; Brust, P.; et al. (6 authors)

Distribution and kinetics of the Kv1.3-blocking peptide HsTX1[R14A] in experimental rats

Bergmann, R.; Kubeil, M.; Zarschler, K.; Chhabra, S.; Tajhya, R. B.; et al. (10 authors)

In vivo examination of an injectable hydrogel system crosslinked by peptide-oligosaccharide interaction in immunocompetent nude mice

Tondera, C.; Wieduwild, R.; Röder, E.; Werner, C.; Zhang, Y.; et al. (6 authors)

Development of highly affine and selective fluorinated cannabinoid receptor type 2 ligands

Moldovan, R.-P.; Hausmann, K.; Deuther-Conrad, W.; Brust, P.

Development of Fluorinated Non-Peptidic Ghrelin Receptor Ligands for Potential Use in Molecular Imaging

Moldovan, R.-P.; Els-Heindl, S.; Worm, D. J.; Kniess, T.; Kluge, M.; et al. (9 authors)

PET Imaging of α7 Nicotinic Acetylcholine Receptors: A comparative study of [18F]ASEM and [18F]DBT-10 in non-human primates, and further evaluation of [18F]ASEM in humans

Hillmer, A. T.; Li, S.; Zheng, M.-Q.; Scheunemann, M.; Lin, S.-F.; et al. (17 authors)

The spatial coefficient of variation in arterial spin labeling cerebral blood flow images

Mutsaerts, H. J.; Petr, J.; Václavů, L.; van Dalen, J. W.; Robertson, A. D.; et al. (10 authors)

Retargeting of T lymphocytes to PSCA- or PSMA positive prostate cancer cells using the novel modular chimeric antigen receptor platform technology “UniCAR”

Feldmann, A.; Arndt, C.; Bergmann, R.; Loff, S.; Cartellieri, M.; et al. (20 authors)

Suppressed Fat Appetite after Roux-en-Y Gastric Bypass Surgery Associates with Reduced Brain µ-opioid Receptor Availability in Diet-Induced Obese Male Rats

Hankir, M.; Patt, M.; Patt, J.; Becker, G.; Rullmann, M.; et al. (14 authors)

Synthesis and in vitro evaluation of new fluorinated quinoline derivatives with high affinity for PDE5: Towards the development of new PET neuroimaging probes

Liu, J.; Maisonial-Besset, A.; Wenzel, B.; Canitrot, D.; Baufond, A.; et al. (8 authors)

The Why and How of Amino Acid Analytics in Cancer Diagnostics and Therapy

Manig, F.; Kuhne, K.; von Neubeck, C.; Schwarzenbolz, U.; Yu, Z.; et al. (8 authors)

Gender Differences in Neural Networks for Color Processing in Mice: A PET/MR Study

Njemanze, P. C.; Kranz, M.; Amend, M.; Wehrl, H.; Brust, P.

Dissociation between brown adipose tissue 18F-FDG uptake and thermogenesis in uncoupling protein deficient mice

Hankir, M. K.; Kranz, M.; Keipert, S.; Andreasen, S.; Kern, M.; et al. (11 authors)

Substrate-dependence of competitive nucleotide pyrophosphatase / phosphodiesterase1 (NPP1)

Lee, S.-Y.; Sarkar, S.; Bhattarai, S.; Namasivayam, V.; de Jonghe, S.; et al. (9 authors)

Predictive Value of Asphericity in Pretherapeutic [111In]DTPA-Octreotide SPECT/CT for Response to Peptide Receptor Radionuclide Therapy with [177Lu]DOTATATE

Wetz, C.; Apostolova, I.; Steffen, I. G.; Hofheinz, F.; Furth, C.; et al. (10 authors)

Human endothelial cell models in biomaterial research

Hauser, S.; Jung, F.; Pietzsch, J.

Synthesis and Preliminary Biological Evaluation of Indol-3-yl-oxoacetamides as Potent Cannabinoid Receptor Type 2 Ligands

Moldovan, R.-P.; Deuther-Conrad, W.; Horti, A. G.; Brust, P.

Radiolabelled polymeric materials for imaging and treatment of cancer: Quo Vadis?

Pant, K.; Sedláček, O.; Nadar, R. A.; Hrubý, M.; Stephan, H.

Hydrous 18F-fluoroethylation – leaving off the azeotropic drying

Kniess, T.; Laube, M.; Steinbach, J.

Adhesion- and stress-related adaptation of glioma radiochemoresistance is circumvented by β1 integrin/JNK co-targeting

Vehlow, A.; Klapproth, E.; Storch, K.; Dickreuter, E.; Seifert, M.; et al. (9 authors)

Cryogel-Supported Stem Cell Factory for Customized Sustained Release of Bispecific Antibodies for Cancer Immunotherapy

Aliperta, R.; Welzel, P. B.; Bergmann, R.; Freudenberg, R.; Berndt, N.; et al. (17 authors)

Gastric Bypass Surgery Recruits a Gut – Striatal Dopamine Pathway to Reduce Fat Appetite in Obese Rats

Hankir, M. K.; Seyfried, F.; Hintschich, C. A.; Diep, T. A.; Kleberg, K.; et al. (17 authors)

Insights into binding of S100 proteins to scavenger receptors: class B scavenger receptor CD36 binds S100A12 with high affinity

Tondera, C.; Laube, M.; Pietzsch, J.

A fluorescence anisotropy-based assay for determining the activity of tissue transglutaminase

Hauser, C.; Wodtke, R.; Löser, R.; Pietsch, M.

Radiosynthesis and biological evaluation of the new PDE10A radioligand [18F]AQ28A

Wagner, S.; Teodoro, R.; Deuther-Conrad, W.; Kranz, M.; Scheunemann, M.; et al. (11 authors)

  • Open Access Logo Journal of Labelled Compounds and Radiopharmaceuticals 60(2017)1, 36-48
    Online First (2016) DOI: 10.1002/jlcr.3471

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