Publications of Institute of Radiopharmaceutical Cancer Research - Year 2012

43 Publications

2012

Cerebral blood flow quantification in the rat: a direct comparison of arterial spin labeling MRI with radioactive microsphere PET

Bos, A.; Bergmann, R.; Strobel, K.; Hofheinz, F.; Steinbach, J.; et al. (6 authors)


Feasibility of estimation of brain volume and 2-deoxy-2-F-18-fluoro-D-glucose metabolism using a novel automated image analysis method: Application in Alzheimer's disease

Musiek, E. S.; Saboury, B.; Mishra, S.; Chen, Y.; Reddin, J. S.; et al. (11 authors)

  • Hellenic Journal of Nuclear Medicine 15(2012), 190-196
    ISSN: 1790-5427

Exploratory prospective trial of hypoxia-specific PET imaging during radiochemotherapy in patients with locally advanced head-and-neck cancer

Zips, D.; Zöphel, K.; Abolmaali, N.; Perrin, R.; Abramyuk, A.; et al. (10 authors)


Flow cytometric cell-based assay to preselect antibody constructs for radionuclide conjugation

Ingargiola, M.; Dittfeld, C.; Runge, R.; Zenker, M.; Heldt, J.-M.; et al. (10 authors)


Synthesis and biological evaluation of a novel Tc-99m cyclopentadienyl tricarbonyl complex ([(Cp-R)Tc-99m(CO)(3)]) for sigma-2 receptor tumor imaging

Chen, X.; Cui, M. C.; Deuther-Conrad, W.; Tu, Y. F.; Ma, T.; et al. (14 authors)


Protein and non-protein biomarkers in melanoma: a critical update.

Tandler, N.; Mosch, B.; Pietzsch, J.


Functional arterial spin labeling: Optimal sequence duration for motor activation mapping in clinical practice

Raoult, H.; Ferré, J.-C.; Petr, J.; Bannier, E.; Stamm, A.; et al. (7 authors)


Synthesis, in silico, in vitro, and in vivo investigation of 5-[11C]methoxy-substituted sunitinib, a tyrosine kinase inhibitor of VEGFR-2

Caballero, J.; Muñoz, C.; Alzate-Morales, J. H.; Cunha, S.; Gano, L.; et al. (8 authors)


Cellular and molecular properties of 90Y-labeled cetuximab in combination with radiotherapy on human tumor cells in vitro

Saki, M.; Toulany, M.; Sihver, W.; Zenker, M.; Heldt, J.-M.; et al. (10 authors)


18F-Labeled phosphopeptide-cell-penetrating peptide dimers with enhanced cell uptake properties in human cancer cells

Richter, S.; Bouvet, V.; Wuest, M.; Bergmann, R.; Steinbach, J.; et al. (8 authors)


Synthesis and cytotoxicity of pyridine and quinoline oxorhenium(V) complexes with tridentate (NS2, S-3)/monodentate (s) coordination

Segal, I.; Zablotskaya, A.; Kniess, T.; Shestakova, I.


18F-labelled CCR1-receptor antagonist is not suitable for imaging of Alzheimer's disease

Beuthien-Baumann, B.; Holthoff, V.; Mäding, P.; Bergmann, R.; Pawelke, B.; et al. (9 authors)


Cannabinoid Receptor Type 2 (CB2) Selective N-Aryl-oxadiazolyl-propionamides: Synthesis, Radiolabeling, Molekular Modelling and Biological Evaluation

Rühl, T.; Deuther-Conrad, W.; Fischer, S.; Günther, R.; Hennig, L.; et al. (7 authors)


Synthesis and crystal structure of benzyl[(1S)-1-(5-amino-1,3,4-oxadiazol-2-yl)-2-phenylethyl]carbamate

Löser, R.; Nieger, M.; Gütschow, M.


Combined PET/MR systems: an overview and comparison of currently available options

Herzog, H.; van den Hoff, J.

  • Quarterly Journal of Nuclear Medicine and Molecular Imaging 56(2012), 247-267
    ISSN: 1824-4785

Improved anatomic visualization of a glomus caroticum tumour within the carotic bifurcation with combined 68Ga-DOTATATE PET/MRI

Beuthien-Baumann, B.; Platzek, I.; Lauterbach, I.; van den Hoff, J.; Schramm, G.; et al. (8 authors)


Fluorine-18-Radiolabeling and Radiopharmacological Characterization of a Benzodioxolylpyrimidine as a Radiotracer Targeting the Receptor Tyrosine Kinase EphB4

Mamat, C.; Mosch, B.; Neuber, C.; Köckerling, M.; Bergmann, R.; et al. (6 authors)


Novel 7α-alkoxy-17α-(4’-halophenylethynyl)estradiols as potential SPECT/PET imaging agents for estrogen receptor expressing tumors: synthesis and binding affinity evaluation

Neto, C.; Oliveira, M. C.; Gano Fernanda Marques, M. L.; Yasuda, T.; Thiemann, T.; et al. (7 authors)


Synthesis and characterization of novel tetrahedral copper(I) complexes comprising tridentate PNP-aminodiphosphines and tetradentate PN(X)P-substituted aminodiphosphines (X = O, S)

Peruzzo, V.; Pretzsch, C.; Tisato, F.; Porchia, M.; Refosco, F.; et al. (10 authors)


Synthesis, in vitro and in vivo characterization of novel 99mTc-‘4+1’-labeled 5-nitroimidazole derivatives as potential agents for imaging hypoxia

Giglio, J.; Fernández, S.; Pietzsch, H.-J. D.; Dematteis, S.; Moreno, M.; et al. (8 authors)


Design, Evaluation, and Comparison of Ghrelin Receptor Agonists and Inverse Agonists as Suitable Radiotracers for PET Imaging

Chollet, C.; Bergmann, R.; Pietzsch, J.; Beck-Sickinger, A. G.


Irradiation affects cellular properties and Eph receptor expression in human melanoma cells

Mosch, B.; Pietzsch, D.; Pietzsch, J.


A method for model-free partial volume correction in oncological PET

Hofheinz, F.; Langner, J.; Petr, J.; Beuthien-Baumann, B.; Oehme, L.; et al. (8 authors)


Radioiodinated sunitinib as a potential radiotracer for imaging angiogenesis - radiosynthesis and first radiopharmacological evaluation of 5-[125I]Iodo-sunitinib

Kuchar, M.; Oliveira, M. C.; Gano, L.; Santos, I.; Knieß, T.


Radiohalogenated 4-anilinoquinazoline-based EGFR-TK inhibitors as potential cancer imaging agents

Neto, C.; Fernandes, C.; Oliveira, M. C.; Gano, L.; Mendes, F.; et al. (7 authors)


Ecto-ATPase inhibition: ATP and adenosine release under physiological and ischemic in vivo conditions in the rat striatum

Melani, A.; Corti, F.; Stephan, H.; Müller, C. E.; Donati, C.; et al. (8 authors)


Study of differences in the VEGFR2 inhibitory activities between semaxanib and SU5205 using 3D-QSAR, docking, and molecular dynamics simulations

Munoza, C.; Adasmea, F.; Alzate-Morales, J. H.; Vergara-Jaquea, A.; Kniess, T.; et al. (6 authors)


Radiolabeled small molecule inhibitors of VEGFR – recent advances

Kniess, T.


Module-assisted preparation of 64Cu with high specific activity

Thieme, S.; Walther, M.; Pietzsch, H.-J.; Henniger, J.; Preusche, S.; et al. (7 authors)


SUV-measurements and patient-specific corrections thereof in pediatric Hodgkin-lymphoma: Is there a benefit for PPV in early response assessment by FDG-PET?

Furth, C.; Meseck, R. M.; Steffen, I. G.; Schoenberger, S.; Denecke, T.; et al. (12 authors)


Automatic volume delineation in oncological PET. Evaluation of a dedicated software tool and comparison with manual delineation in clinical data sets

Hofheinz, F.; Pötzsch, C.; Oehme, L.; Beuthien-Baumann, B.; Steinbach, J.; et al. (7 authors)


Synthesis and Molecular Structure of tert-Butyl 4-(2-tert-butoxy-2-oxoethyl)piperazine-1-carboxylate

Mamat, C.; Flemming, A.; Köckerling, M.


The Synthesis and Molecular Structure of 2-(4-Methoxybenzyl)-4-nitro-2H-indazole

Ebert, K.; Köckerling, M.; Mamat, C.


Specific targeting of hypoxic tumor tissue with nitroimidazole-peptide conjugates

Splith, K.; Bergmann, R.; Pietzsch, J.; Neundorf, I.


Pyrrolovesamicols - Synthesis, structure and VAChT binding of two 4-fluorobenzoyl regioisomers

Wenzel, B.; Li, Y.; Kraus, W.; Sorger, D.; Sabri, O.; et al. (7 authors)


The Molecular Structure of 1,2:5,6-Di-O-isopropylidene-3-O-toluenesulfonyl-a-D-glucofuranose

Mamat, C.; Peppel, T.; Köckerling, M.


Imaging of the brain serotonin transporters (SERT) with 18F-labelled fluoromethyl-McN5652 and PET in humans

Hesse, S.; Brust, P.; Mäding, P.; Becker, G.-A.; Seese, A.; et al. (17 authors)


Development of radioligands for α7-nAChR imaging with positron emission tomography

Brust, P.; Peters, D.; Deuther-Conrad, W.


Synthesis, radiofluorination and pharmacological evaluation of fluoromethyl substituted spirocyclic PET tracers for labeling of σ1 receptors in the central nervous system and comparison with longer homologues

Maisonial, A.; Grosse Maestrup, E.; Wiese, C.; Hiller, A.; Schepmann, D.; et al. (9 authors)


Radiosynthesis and Radiotracer Properties of a 7-(2-[F-18]Fluoroethoxy)-6-methoxy-pyrrolidinylquinazoline for Imaging of Phosphodiesterase 10A with PET

Funke, U.; Deuther-Conrad, W.; Schwan, G.; Maisonial, A.; Scheunemann, M.; et al. (9 authors)


Site-selective radiolabeling of peptides by 18F-fluorobenzoylation with [18F]SFB in solution and on solid phase - a comparative study

Kuchar, M.; Pretze, M.; Knieß, T.; Steinbach, J.; Pietzsch, J.; et al. (6 authors)


Effect of leukotriene inhibitors on evolution of experimental brain contusions

Voigt, C. L. M.; Donat, C. K.; Härtig, W.; Förschler, A.; Arendt, T.; et al. (7 authors)


Radiosynthesis of a 18F-labeled 2,3-diarylsubstituted indole via McMurry coupling for functional characterization of cyclooxygenase-2 (COX-2) in vitro and in vivo

Kniess, T.; Laube, M.; Bergmann, R.; Graf, F.; Steinbach, J.; et al. (7 authors)


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